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Vertex Pharmaceuticals Reports Robust First Quarter 2024 Results: A Closer Look at Growth and Future Prospects

Vertex Pharmaceuticals Reports Robust First Quarter 2024 Results: A Closer Look at Growth and Future Prospects

Boston, May 6, 2024 – Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced its financial results for the first quarter of 2024, displaying significant growth and setting a promising outlook for the remainder of the year. The company's strong financial performance and strategic advancements underline its position as a leader in the biotechnology industry.

Impressive Financial Growth in Q1 2024

Vertex reported a substantial 13% increase in product revenue, reaching $2.69 billion for the first quarter of 2024 compared to the same period last year. This growth was primarily fueled by the successful uptake of TRIKAFTA/KAFTRIO in new markets and younger patient demographics. Notably, U.S. revenues rose by 8% to $1.52 billion, while international revenues saw a remarkable 21% increase to $1.17 billion.

The company also reported a decrease in combined GAAP and Non-GAAP R&D, Acquired IPR&D, and SG&A expenses, reflecting efficient management and the completion of certain developmental milestones. These factors contributed to a significant rise in both GAAP and Non-GAAP net income, which increased by 57% and 56% respectively, compared to the first quarter of 2023.

Strategic Advancements and Regulatory Milestones

Vertex continues to innovate with multiple products in the pipeline and several regulatory milestones achieved in the quarter. Key highlights include:

  • Regulatory Progress: Vertex has made substantial advancements with the vanzacaftor triple combination for cystic fibrosis (CF), having submitted regulatory filings to the FDA and EMA. Additionally, the company initiated a rolling submission for suzetrigine (VX-548) for moderate-to-severe acute pain, with completion expected this quarter.
  • Acquisition of Alpine Immune Sciences: Vertex announced the acquisition of Alpine Immune Sciences, a strategic move that includes the promising Phase 3-ready asset, povetacicept, for IgA nephropathy (IgAN). This acquisition is poised to enhance Vertex's portfolio and drive long-term growth.

Continued Focus on Cystic Fibrosis and Expansion into New Therapeutic Areas

Vertex's commitment to addressing CF remains strong, with ongoing efforts to expand patient access to TRIKAFTA/KAFTRIO and other treatments. The company also highlighted its expansion into other serious diseases, including sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT), through the successful launch of CASGEVY in various global markets.

Financial Outlook for 2024

Looking ahead, Vertex reiterated its full-year 2024 financial guidance, with product revenue expected to be between $10.55 and $10.75 billion. The forecast reflects continued growth in CF treatments and the anticipated launch of new therapies. Non-GAAP R&D, Acquired IPR&D, and SG&A expenses are projected to be between $4.3 billion and $4.4 billion.

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